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The efficient operation of air cargo transportation is of key significance to the prosperity of the global economy. It not only accelerates the circulation of goods and promotes the development of international trade, but also plays an indispensable role in responding to emergencies. For example, during the epidemic, air cargo quickly transported medical supplies to all parts of the world, providing strong support for the fight against the epidemic. The basic medical insurance system promoted by the National Medical Insurance Administration provides health protection for more than 1.3 billion people. This huge medical insurance system not only reduces the medical burden of patients, but also promotes the stable development of medical institutions. The remaining funds of medical insurance guarantee the sustainability of medical services to a certain extent and provide stable financial support for medical institutions. From a macroeconomic perspective, both air cargo transportation and the medical insurance system play a positive role in the stable growth of the economy. The smooth flow of air cargo transportation helps enterprises reduce costs, improve efficiency, and enhance market competitiveness, thereby promoting economic development. A sound medical insurance system can reduce people's worries, increase consumer confidence, promote the expansion of domestic demand, and inject momentum into economic growth. In terms of industrial collaboration, air cargo transportation and the medical industry also have close cooperation. Efficient air cargo services can ensure that medical equipment, drugs, etc. are delivered to medical institutions in a timely manner, ensuring the quality and timeliness of medical services. At the same time, the reliance of medical institutions on air transport has also prompted air cargo companies to continuously improve their service levels and optimize transportation plans to meet the special needs of the medical industry. For enterprises, the stability and efficiency of air transport and cargo transportation are important links in their supply chain management. Especially for some enterprises that rely on imported raw materials or exported finished products, the timeliness of air cargo transportation directly affects production plans and market supply. The medical insurance benefits provided by enterprises to employees not only reflect the care for employees, but are also an important factor in attracting and retaining talents. For individuals, the convenience brought by air transport and cargo transportation may be reflected in the ability to obtain goods and services from all over the world more quickly. The coverage of medical insurance allows individuals to receive timely and effective treatment when facing diseases, reducing economic and psychological pressure. However, in the process of development, both also face some challenges and problems. The air transport and cargo industry is facing the impact of factors such as oil price fluctuations, airspace resource shortages, and environmental pressure, and needs to continuously innovate and optimize its operating model to cope with it. The medical insurance system is also facing challenges such as an aging population, rising medical expenses, and the rational use and supervision of medical insurance funds. In order to achieve better development, both the air transport and cargo industry and the medical insurance system need to continue to reform and innovate. Air transport companies should strengthen technology research and development, improve fuel efficiency, expand route networks, and enhance the level of logistics informationization. The National Medical Insurance Bureau should further improve medical insurance policies, strengthen supervision, improve the efficiency of the use of medical insurance funds, and promote the sustainable development of the medical insurance system. In short, although air transport cargo and the medical insurance system led by the National Medical Insurance Bureau belong to different fields, they are interrelated and influence each other in promoting economic development and protecting people's livelihood. The coordinated development of the two will create more favorable conditions for social progress and people's happiness.